Compound in Salmon Switches on 'Longevity Gene' in Mice
Astaxanthin, a red pigment found mostly in marine life, can switch on a variation of the FOXO3 gene, which protects against aging, say scientists from the University of Hawaii.
“All of us have the FOXO3 gene, which protects against aging in humans,” said Bradley Willcox, M.D. “But about one in three persons carry a version of the FOXO3 gene that is associated with longevity.
“By activating the FOXO3 gene common in all humans, we can make it act like the ‘longevity’ version. Through this research, we have shown that astaxanthin ‘activates’ the FOXO3 gene,” said Willcox.
In the study, mice were fed either normal food or food containing a low or high dose of an astaxanthin compound called CDX that was developed by Cardax, a Honolulu-based life sciences company.
The animals that received the higher amount of astaxanthin showed a significant increase in the activation of the FOXO3 gene in their heart tissue.
“We found a nearly 90 percent increase in the activation of the FOXO3 ‘Longevity Gene’ in the mice fed the higher dose of the astaxanthin compound,” said Richard Allsopp, Ph.D.
The researchers hope further research will confirm astaxanthin’s role in helping alleviate the effects of aging in humans.
Astaxanthin is a red pigment found mostly in marine life and is responsible for giving salmon, lobster, and other animals their reddish coloring. Studies have found that astaxanthin has a powerful ability to neutralize the free radicals in the body that cause aging by damaging cells. Laboratory studies have found that astaxanthin has 6,000 times the ability of vitamin C and 550 times the power of vitamin E to combat oxidative damage.
Astaxanthin is most abundant in wild Pacific sockeye salmon with 3.2 milligrams in a 3-ounce serving. Farmed rainbow trout comes in second at 2.1 milligrams in a 3-ounce serving. Other natural sources include algae, lobster, crawfish, and krill.
Professional Scope of Practice *
The information herein on "Compound in Salmon Switches on 'Longevity Gene' in Mice" is not intended to replace a one-on-one relationship with a qualified health care professional, or licensed physician, and is not medical advice. We encourage you to make your own healthcare decisions based on your research and partnership with a qualified healthcare professional.
Blog Information & Scope Discussions
Our information scope is limited to Chiropractic, musculoskeletal, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.
We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.
Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.*
Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.
We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez DC or contact us at 915-850-0900.
We are here to help you and your family.
Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, ATN*
Licensed in: Texas & New Mexico*
Dr. Alex Jimenez DC, MSACP, CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card