The gut-brain connection is essential to the body. When either one is feeling disrupted it can cause problems that can lead to chronic illness. Read More
Back and low back pain can strike without warning. It can come from bending over or lifting something and then you're stuck, unable to move. However, muscle spasm in the low back is a common occurrence. Eight out of 10 adults will experience back spasm along with back pain during their lives. The cause of back pain and… Read More
When compared to other central nervous system (CNS) health issues, chronic neurodegenerative diseases can be far more complicated. Foremostly, because the compromised mitochondrial function has been demonstrated in many neurodegenerative diseases, the resulting problems in energy sources are not as severe as the energy collapse in ischemic stroke. Therefore, if excitotoxicity contributes to neurodegeneration, a different time of chronic excitotoxicity… Read More
Sacroiliac joint dysfunction is known to cause low back pain, but diagnosing can be hard for some doctors. Especially those that do not have a great deal of experience in sacroiliac joint pain. However, chiropractors specialize in this area as the SI joint is an important part of the musculoskeletal system. SI joint dysfunction and pain can involve one or both… Read More
Excitotoxicity is characterized as an acute insult which causes nerve cell death due to the excessive activation of iGluRs. Acute excitotoxicity plays a fundamental role in a variety of central nervous system (CNS) health issues, including cerebral ischemia, TBI, and status epilepticus. The mechanisms for acute excitotoxicity are different for every health issue. With brain ischemia, L-glutamate-associated and… Read More
Autoimmune disease is the disease of the modern era. It is a condition where the body’s immune system mistakenly attacks the body. Read More
Today Dr. Alex Jimenez of El Paso, Texas, informs us what does SIBO do to the intestinal barrier. Read More
Today, Dr. Alex Jimenez of El Paso, Texas discuss what the role is the Nrf2 cell. Read More
State of Texas Office of the Governor As far too many Americans and Texans know, chronic pain remains a huge public health problem and one of the most prevalent reasons why people seek medical care. Chronic pain negatively impacts many aspects of a person’s life as well as the lives of their families, friends, and caregivers. It is essential… Read More
Previous research studies suggest that L-aspartate, like L-glutamate, triggers excitatory activity on neurons. L-aspartate functions with L-glutamate in the synaptic vesicles of asymmetric excitatory synapses. But, the total concentration of these in the human brain (0.96-1.62 μmol/gram wet weight), their extracellular concentrations in the cortex as measured by microdialysis (1.62 μM for L-aspartate and 9.06 μM for L-glutamate) and their… Read More
The term excitotoxicity was first employed to demonstrate the capability of L-glutamate, in addition to structurally-associated amino acids, to destroy nerve cells, a process which has been suggested to occur in acute and chronic health issues of the central nervous system (CNS). Excitotoxicity is caused by the excess stimulation of iGluRs into a characteristic loss of cell bodies and dendrites… Read More
Hormone testing can now be done by using top of the line integrative methods and techniques. Read More
Today, Dr. Alex Jimenez of El Paso, Texas inform us about mycotoxin exposure. Read More
Sciatica doesn’t have to prevent you from being able to travel. Sometimes a journey can create a series of challenges for people with sciatic nerve pain in the low back and leg. A common issue among individuals is to prevent sciatica from flaring up when on the road or in the air. A solution for this is to find ways… Read More
L-glutamate is one of the main excitatory neurotransmitters in the human brain and it plays an essential role in practically all activities of the nervous system. In the following article, we will discuss the general principles of L-glutamate signaling in the brain. Then, we will demonstrate this scheme by describing the different pools of extracellular glutamate, including the synaptic, the… Read More