Neurophysiology of pain: Pain defined is the unpleasant sensation that accompanies injury or near injury to tissues, though it can also occur in the absence of such damage if the nociception system is not functioning. Nociception means the system that carries pain signals of injury from the tissues. This is the physiological incident that comes with pain.
Table of Contents
“Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage”.
(The International Association for the Study of Pain)
These drugs can effect:
The sensory system that can be divided into two divisions:
These two systems have different receptors and pathways in the PNS & CNS
… which can cause the membrane potential at the free nerve ending (nociceptor) to produce an action potential.
Silverthorn
Nerve fibers are classified according to the:
– (1) diameter of the nerve fiber and
– (2) whether myelinated or not.
Nociceptive signals are sent to the spinal cord and then to different parts of the brain where sensation of pain is processed.
There are a pathways/regions for assessing the:
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