Dr. Alex Jimenez, El Paso's Chiropractor
I hope you have enjoyed our blog posts on various health, nutritional and injury related topics. Please don't hesitate in calling us or myself if you have questions when the need to seek care arises. Call the office or myself. Office 915-850-0900 - Cell 915-540-8444 Great Regards. Dr. J

The Latest Guidelines: Male Hormones | Part 1


Hormones in the body control the organs and the entire body system, from the endocrine system to the body’s temperature. When hormones get out of balance, they can lead to chronic problems.  Over the last decade, many of our patients have asked great complex and insightful questions about hormone replacement therapies. We refer patients to skilled and qualified providers specialized in hormone wellness services.  To that end, and when appropriate, we advise our patients to refer to our associated medical providers based on their examination.  We find that education is the key to asking good questions to our providers. We provide this information as an educational service only. Disclaimer

What Is Hormone Replacement Therapy?

Hormone replacement therapy can help older males replenish testosterone hormone levels. Another thing that hormone replacement therapy can provide is that it can reduce the levels of androgens in the body to prolong the process of prostate cancer while also lowering adrenal gland over-production.

Low T: The Clinical Problem

Hypogonadism affects 30% of men aged 40-79

– A gradual, age-associated decline in serum total testosterone levels begins in men
in their mid-30s and continues at an average rate of 1.6% per year

  • Symptoms
    – Fatigue / Cognitive function decline
    – Decreased libido
    – ED
    – Depression, irritability, decreased sense of well-being
    – Decreased muscle mass / increased body fat
    – Decreased bone mineral density

New Guidelines Presented at the American Academy of Anti-Aging.


  • Synthesized directly from cholesterol
    – Precursor to all other sex hormones
  • Levels start to decline around age 30
  • Functions to:
    – Enhance nerve transmission and memory
    – Improve energy and sleep
    – Increase stress resistance
    – Mood elevation– Reduce pain and inflammation
  •  Deficiency associated with:
    – Depression
    – Fatigue
    – Inability to deal with stress
    – Insomnia
    – Lack of focus
    – Memory decline

Pregnenolone Dosing

  • Pregnenolone SR to start at 10mg per day and
    titrate up slowly until you reach a blood level of 100
    which is optimal
  • SR form more physiological
  • Can cause agitation and anxiety if titrate too fast or if
    the dose is high for patient


  • Made by the adrenal glands
  • Precursor to androstenedione
  • Levels start to decline in men around age 60
  • Functions to balance estrogen
    – Inhibits aromatase and 5-alpha reductase
    – Antagonizes stimulatory effects of estrogen on the prostate gland
    and lowers PSA
    – Stimulates anti-tumor antigen, p53, to prevent prostate cancer

Progesterone Dosing

  • In men, you start with 3-5mg topically daily
  • Usually added to testosterone/Chrysin cream
  • Can use capsule form if the patient has sleep
    issues. Dose range 5-15mg oral


  • Made by the adrenal glands
  • The precursor to estrogen and testosterone
  • Production declines with age
  • Protective effect against:
    – Cancer, diabetes, obesity, high cholesterol, heart disease, and
    autoimmune diseases
  • Symptoms of deficiency:
    – Decreased energy & muscle strength, difficulty dealing with stress,
    increase risk of infection, irritability, joint soreness, and weight gain

Actions of DHEA

  • Prohormone for sex steroids
  • Anti-glucocorticoid
  • Immune supporting
  • Anti-atherogenic lowers serum triglycerides
  • Enhances insulin sensitivity; anti-obesity effect
  • Maintains tissue strength and repair, supports bone density
  • Neuroprotective; enhances memory
  • Promotes a sense of well-being
  • Libido enhancing

DHEA Dosing

Replacement linked with an improved libido, mood, erectile function

  • Improves neural protection, especially when Cortisol is high
  • Men need 25-50mg per day
  • SR form is more physiological
  • DHEA is a large molecule, and therefore, it is not well absorbed topically
  • Side effects include oily skin, hirsutism, acne
  • K-DHEA form can be used if concerned for cancer and want to bypass
    hormonal byproducts


  • Common precursor of male and female sex hormones
    – Converted to testosterone through 17ơ-hydroxysteroid
    – Converted to estrogen through the aromatase
  • Found in testes and adrenal glands
  • Short half-life
  • No reliable studies on benefits

Dihydrotestosterone (DHT)

  • Most potent naturally occurring androgen
    – 3 times more potent than testosterone
  • Synthesized from the conversion of testosterone
    through 5-alpha reductase
  • Responsible for formation of male sex-specific
    characteristics and development of male genitalia and
    – Low levels can affect sexual function and libido, muscle
  • Elevated levels can cause:
    – Hirsutism
    – Male pattern baldness
    – BPH
    – Prostate cancer
  • 25% secreted by testes, 75% from
    bioconversion from T in liver, kidney, muscle,
    prostate, and skin
  • The blood concentration of DHT is 10% that of T but at least twice as potent due to increased affinity
    for androgen receptor; cannot be aromatized to
  • Produced in utero is responsible for the development
    of male sex characteristics
  • A primary contributing factor in androgenic
    alopecia, benign prostatic hypertrophy, hirsutism
    in women


  • Made in muscle, skin, and adipose tissue
  • Adequate levels protect against bone fractures,
    and maintain cognitive function
  • Excess associated with:
    – Gynecomastia
    – Decreased sex drive/erectile dysfunction
    – The doubled risk of stroke
    – Higher rates of heart attack, peripheral artery disease,
    and coronary atherosclerosis
    – Insulin resistance
    – Rheumatoid arthritis
    – BPH
    – Prostate cancer


Testosterone is the principal male hormone in males that are important for normal males’ sexual development and functions.

  • Principal male hormone
  • Anabolic steroid produced from cholesterol
  • Primarily secreted in the testes and small amounts secreted
    from the adrenal glands
  • Functions:
    – Anabolic effects: increased muscle mass, bone density, and
    bone maturation
    – Androgenic effects: development of sex organs, deepening
    of voice, hair growth

Factors Contributing to Testosterone Decline

Many factors can contribute to the decline in male testosterone levels in the body.

  • AGE
  • Diet and insulin resistance
  • Stress levels/cortisol demand
  • Toxin exposure
  • Depression
  • Insomnia
  • Decreased muscle mass and strength
  • Osteoporosis
  • Decreased hair density
  • Erectile dysfunction

Male Diminished Libido

  •  Low Bioavailable Testosterone
    • Age-Related Testosterone Decline
      – (Leydig Cell Dies Every 4 Seconds)
    •  Obesity – Lowers Testosterone
    • Beta-Blockers, Statins, NSAIDs, SSRIs
    • High SHBG
      – Excess Prolactin
    • Inhibits Dopamine Release
    • Responsible for the Refractory Period

Andropause Contributes to Many Diseases

  • Diabetes/Metabolic Syndrome
  • Brain (Dementia, Alzheimer’s)
  • Heart (MIbs)
  • Frailty Syndrome/Sarcopenia
  • Bone (Osteoporosis)
  • Inflammation

Testosterone Decline

  • Testosterone declines with age, beginning in the
    early 30bs
  • By age 40, levels naturally decline by >1% per
  • Testosterone production declines due to:
    – Increasing SHBG
    – Decreasing LH
    – Decreased Leydig cell activity
  • During the time between 25 to 75 years old:
    – 30% decrease in Total Testosterone
    – 50% decrease in Bioavailable Testosterone
  • Half of the healthy men between the ages of 50-70 years will
    have a bioavailable testosterone level below the lowest
    level was seen in healthy men who are 20-40 years of age.

TD and Metabolic Syndrome

When the testosterone hormone levels are low in a male’s body, it can also cause the body to develop metabolic syndrome.

  •  The increased risk of insulin resistance and
    metabolic syndrome is not due to changes in SHBG as the
    inverse relationship with low testosterone persists when
    looking at free T
  • Weight loss improves levels of both free and
    total T proportionate to the amount of weight
  • TD is associated with weight gain; weight loss
    improves T levels
  • ADT is associated with increased BMI and
    decreased lean body mass (compared to men
    who had surgery and no ADT for prostate cancer)

Things That Can Increase Insulin

  • High carbohydrate diet
  • Increased stress
  • Decreased estrogens
  • Increased testosterone
  • Insomnia
  • Increased DHEA
  • Decreased thyroid hormone
  • Excessive progesterone
  • Lack of exercise
  • High chronic stress causes low DHEA and low testosterone
  • Cortisol will act as an anti-testosterone in the body


All in all, the effects of a healthy male’s hormone levels can be affected when the body is not taken care of or due to natural causes. Low testosterone levels can cause prolonged effects like metabolic syndrome and insulin resistance. By combining a healthy diet and regular exercise can help the body achieve its overall wellness.


Again, I Welcome You 👊🏻.

Our Purpose & Passions: I am a Doctor of Chiropractic specializing in progressive, cutting-edge therapies and functional rehabilitation procedures focused on clinical physiology, total health, practical strength training, and complete conditioning. We focus on restoring normal body functions after neck, back, spinal and soft tissue injuries.

We use Specialized Chiropractic Protocols, Wellness Programs, Functional & Integrative Nutrition, Agility & Mobility Fitness Training, and Rehabilitation Systems for all ages.

As an extension to effective rehabilitation, we too offer our patients, disabled veterans, athletes, young and elder a diverse portfolio of strength equipment, high-performance exercises, and advanced agility treatment options. We have teamed up with the cities premier doctors, therapists,s, and trainers to provide high-level competitive athletes the possibilities to push themselves to their highest abilities within our facilities.

We’ve been blessed to use our methods with thousands of El Pasoans over the last three decades allowing us to restore our patients’ health and fitness while implementing researched non-surgical methods and functional wellness programs.

Our programs are natural and use the body’s ability to achieve specific measured goals, rather than introducing harmful chemicals, controversial hormone replacement, unwanted surgeries, or addictive drugs. We want you to live a functional life that is fulfilled with more energy, a positive attitude, better sleep, and less pain. Our goal is to ultimately empower our patients to maintain the healthiest way of living.

With a bit of work, we can achieve optimal health together, no matter the age or disability.

Join us in improving your health for you and your family.

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Phone: 915-850-0900

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Phone: 915-412-6677

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The information herein is not intended to replace a one-on-one relationship with a qualified health care professional, licensed physician, and is not medical advice. We encourage you to make your own health care decisions based on your research and partnership with a qualified health care professional. Our information scope is limited to chiropractic, musculoskeletal, physical medicines, wellness, sensitive health issues, functional medicine articles, topics, and discussions. We provide and present clinical collaboration with specialists from a wide array of disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the musculoskeletal system’s injuries or disorders. Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and support, directly or indirectly, our clinical scope of practice.* Our office has made a reasonable attempt to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request. We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez or contact us at 915-850-0900 Read More…

Dr. Alex Jimenez DC, MSACP, CCST, IFMCP*, CIFM*, CTG* 

email: coach@elpasofunctionalmedicine.com
phone: 915-850-0900
Licensed in Texas & New Mexico