People who complain that they only have to smell food to gain weight may be right. Researchers at the University of California, Berkeley, found that obese mice who lost their sense of smell also lost weight. That part of the study was no surprise. But the strange part of the study found that mice that retained their sense of smell ballooned to twice their normal weight by eating the same amount of fatty food as the mice with no sense of smell.
Stranger still is that mice with a superior sense of smell gained even more weight on the same high-fat diet than the mice with a normal sense of smell.
The findings, which were published in the journal Cell Metabolism, suggest that the odor of what we eat may play an important role in how the body deals with calories. If you can’t smell your food, you may burn it rather than store it. But simply being able to smell your food may pack on the pounds.
Scientists know that humans who lose their sense of smell due to age, strokes, or diseases such as Parkinson’s, often become anorexic. They theorized that the loss of pleasure in eating can lead to depression, which can cause loss of appetite. But the new study suggests that the loss of smell itself plays a role in how the body uses energy.
For the study, researchers used gene therapy to destroy olfactory neurons in the noses of adult mice. They spared stem cells, however, so that the loss of smell was only temporary and lasted for about three weeks before the olfactory neurons re-grew.
The smell-deficient mice rapidly burned calories by reregulating their sympathetic nervous system, which is known to increase fat burning. The mice turned their beige fat cells, the subcutaneous fat storage cells that accumulate around our thighs and midriffs, into brown fat cells, which burn fatty acids to produce heat.
Some mice turned almost all of their beige fat into brown fat, becoming lean, mean fat-burning machines.
In these mice, white fat cells — the storage cells that cluster around our internal organs and are associated with many health problems — also shrank in size.
Although it would be a drastic step to eliminate smell in humans wanting to lose weight, Andrew Dillin, senior author of the study, said it might be a viable alternative for the morbidly obese contemplating stomach stapling or bariatric surgery.
“For that small group of people, you could wipe out their smell for maybe six months and then let the olfactory neurons grow back, after they’ve got their metabolic program rewired,” he said.
One problem is that the loss of smell was accompanied by a large increase in levels of the hormone noradrenaline, which is a stress response tied to the sympathetic nervous system. In humans, such a prolonged rise in this hormone could cause a heart attack.
But stomach stapling and bariatric surgery are also associated with problems. A study published in Surgery for Obesity and Related Diseases found that one in five patients who undergo bariatric surgery for weight loss is likely to develop problems with alcohol.
The information herein on "Does Smelling Food Make You Fat?" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.
Our information scope is limited to Chiropractic, musculoskeletal, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.
We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.
Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*
Our office has reasonably attempted to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.
We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.
We are here to help you and your family.
Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card