Upping the intake of soy protein may help fight inflammatory bowel disease (IBD), say Penn State researchers whose study included both mice and cultured human colon cells.
Inflammatory bowel diseases, which include ulcerative colitis and Crohn’s disease, are characterized by either continuous or periodic inflammation of the colon and are a significant risk factor for colon cancer.
For their study, researchers removed protein sources from the diets of the mice and substituted soy-protein concentrate. The soy equaled about 12 percent of their diet.
“We didn’t want to get carried away with using doses that were really high and would crowd out all the other protein that was there,” said researcher Zachary Bitzer. “Instead, we wanted to find a scenario that was going to fit into a more human-relevant situation.”
The dietary soy-protein at the 12-percent dose level improved body-weight loss and swelling of the spleen in the mice with induced inflammatory bowel disease.
“Soy-protein concentrate mitigates markers of colonic inflammation and loss of gut barrier function in the mice with induced IBD,” said researcher Amy Wopperer.
Followup studies will focus on whether the results translate to people. Because soy protein is a widely used food ingredient — often used as a meat substitute and commonly referred to as “texturized vegetable proteins” in ingredient lists — the researchers believe human studies could be arranged in the near future.
The study is published in The Journal of Nutritional Biochemistry,
Other studies have found soy to have health benefits. A study from Wayne State University found that compounds in soybeans can make radiation treatment of lung cancer more effective while helping to preserve normal tissue.
Soy isoflavones, a natural component of soybeans, increase the ability of radiation to kill cancer cells by hindering pathways necessary for the cancer cells to survive. At the same time, they act as antioxidants that protect normal cells from radiation-induced toxicity.
“In contrast to drugs, soy is very, very safe,” said Gilda Hillman, Ph.D., professor of radiation oncology at Wayne State University’s School of Medicine. “It’s also readily available, and it’s cheap.”
The information herein on "Soy Protein May Ease Inflammatory Bowel Disease" is not intended to replace a one-on-one relationship with a qualified health care professional or licensed physician and is not medical advice. We encourage you to make healthcare decisions based on your research and partnership with a qualified healthcare professional.
Our information scope is limited to Chiropractic, musculoskeletal, physical medicines, wellness, contributing etiological viscerosomatic disturbances within clinical presentations, associated somatovisceral reflex clinical dynamics, subluxation complexes, sensitive health issues, and/or functional medicine articles, topics, and discussions.
We provide and present clinical collaboration with specialists from various disciplines. Each specialist is governed by their professional scope of practice and their jurisdiction of licensure. We use functional health & wellness protocols to treat and support care for the injuries or disorders of the musculoskeletal system.
Our videos, posts, topics, subjects, and insights cover clinical matters, issues, and topics that relate to and directly or indirectly support our clinical scope of practice.*
Our office has reasonably attempted to provide supportive citations and has identified the relevant research study or studies supporting our posts. We provide copies of supporting research studies available to regulatory boards and the public upon request.
We understand that we cover matters that require an additional explanation of how it may assist in a particular care plan or treatment protocol; therefore, to further discuss the subject matter above, please feel free to ask Dr. Alex Jimenez, DC, or contact us at 915-850-0900.
We are here to help you and your family.
Licensed as a Registered Nurse (RN*) in Florida
Florida License RN License # RN9617241 (Control No. 3558029)
License Compact Status: Multi-State License: Authorized to Practice in 40 States*
Presently Matriculated: ICHS: MSN* FNP (Family Nurse Practitioner Program)
Dr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
My Digital Business Card